The smart Trick of ceesdekker That No One is Discussing
The smart Trick of ceesdekker That No One is Discussing
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Employing solitary-molecule optical and AFM imaging and force-spectroscopy procedures, we search for to unravel the mechanistic areas of the construction and dynamics of chromosomes. Our research pursuits include things like:
You regularly get entangled in discussions about science and religion. You've also penned various publications on the topic. Don’t you feel that in some unspecified time in the future We'll know everything and that God’s role is going to be over?
Multicolor imaging from the bacterial nucleoid and mobile division proteins with blue, orange, and in close proximity to-infrared fluorescent proteins
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
2012, discovery that nucleoid occlusion underlies the precision of bacterial cell division; and initially ever review in the dynamics DNA supercoils and the invention of supercoil hopping
The coiled-coil from the human Rad50 DNA maintenance protein is made up of particular segments of increased overall flexibility
Given that 2000 he moved to single-molecule biophysics and nanobiology, with study from DNA supercoiling studies of nucleosomes and DNA maintenance proteins to DNA translocation by nanopores. Just lately his study has centered on finding out cell division with microbes on chip, when his final interest is from the route of recognizing artificial cells.
Atomic drive microscopy shows that vaccinia topoisomerase IB ceesdekker.net generates filaments on DNA in the cooperative manner
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But carbon nanotubes have remained a exploration subject matter of sizeable desire to quite a few. In fact, the outlook on working with carbon nanotubes to develop functional units, in places including radio-frequency electronics, digital electronics and versatile electronics, continues to be vivid.
An integrated microfluidic platform for quantifying drug permeation across biomimetic vesicle membranes
Numerous new phenomena were being learned, and he and his study team proven a number one placement Within this subject of analysis. Dekker and his investigate group found out new physics of nanotubes and also explored the feasibility of molecular electronics. In 1998, they were the 1st to construct a transistor based upon just one nanotube molecule.
One example is, we consider the nucleopore sophisticated, a gateway in between the mobile nucleus plus the cytoplasm. This is an extremely complicated procedure and for that reason tough to study inside of a mobile, so we use biomimetics. We reconstruct holes and after that insert individual things in the nucleopore complicated to check transport as a result of it at The only-molecule level.’
‘I'm pushed by wonder and queries. On a fabric stage I obtain answers in physics, but I encounter my deepest joy with God. That faith also drives my science And just how I manage people today.